Is drag-and-drop not working on Mac between some apps but works fine with others? If only certain applications don’t work correctly with this common mouse function, you should look for answers that relate to the specific software in question. This can interrupt mouse tasks such as dragging and dropping something. Some mice, like the first-generation Apple Magic Mouse, are notorious for constantly disconnecting while you work. Check the buttons for dirt or grime and make sure that the USB plug or cable aren’t damaged.